DR DOUG QUARRY
In today’s edition:
1. New US data shows AstraZeneca vaccine is effective for all adults
2. The vaccine gap is bad for the world
3. Only 20 countries have vaccinated more than 5% of their population
4. Chile is currently giving the most doses per 100 people per day
5. Vaccine scepticism – a luxury of “rich” countries
6. Europe’s vaccine ethics call: Do no harm and let more die?
7. EU has “absolutely no need” for Sputnik V vaccine, Commissioner says
8. Ghana has vaccinated more than 420,000 people against COVID-19 in just two weeks!
9. EU export ban would delay UK COVID-19 vaccine drive by two months
10. WHO Chief: waive COVID-19 vaccine patents to put world on “war footing”

1. New US data shows AstraZeneca vaccine is effective for all adults
The AstraZeneca vaccine has suffered reputational damage due to:
• Mix up in dosing in original trial
• Trying to average results in original trial
• Not enough people > 65 in original trial
• Recent question of causing blood clots (true ethical dilemma)
Results from much-awaited US study (published by AstraZeneca 22 March)
• 100% efficacy against severe or critical disease and hospitalization
• 79% vaccine efficacy at preventing symptomatic COVID-19
• Comparable efficacy result across ethnicity and age
• (80% efficacy in participants aged 65 years and over)
• Favourable reactogenicity and overall safety profile
MORAL: The best vaccine is the one that you have before you have COVID-19!!
2. The vaccine gap is bad for the world
The New York Times reports that:
• “Of the COVID-19 vaccine doses given globally, roughly ¾ have gone to only ten countries. • At least 30 countries have not yet injected a single person.
• Many poorer nations could wait years for their shots.”
“Many countries were relying on the global vaccine program known as COVAX, which was created around the idea that all countries would buy vaccines through a single mechanism, but dozens of wealthy nations went straight to pharmaceutical companies and elbowed the program out of the way.”
3. Only 20 countries have vaccinated more than 5% of their population
4. Chile is currently giving the most doses per 100 people per day
5. Vaccine scepticism – a luxury of “rich” countries
6. Europe’s vaccine ethics call: Do no harm and let more die?
The New York Times reports: “European health agencies this week faced, with millions of lives in the balance, a staggeringly high-stakes incarnation of what ethicists call the trolley problem.”
The Trolley Problem
“Imagine standing at a railway switch. If you do nothing, a trolley barreling down the track will hit three people in its path. If you pull the lever, the trolley will divert to an alternate track with one person. Which option is morally preferable: deliberately killing one person or passively allowing three to die?
“In Europe’s version, German regulators identified seven cases of a rare cerebral blood clot – three of them fatal – out of 1.6 million who had received the AstraZeneca vaccine. Regulators had no proof they were linked. Still, continuing vaccinations might make them responsible for putting a handful of people in harm’s way — like pulling the lever on the trolley tracks.
“Instead, the German authorities withdrew approval for the vaccine. Neighbouring countries followed, waiting for the European Union drug regulator to deem the vaccine safe, which it did on 18 March.”
7. EU has “absolutely no need” of Sputnik V vaccine, commissioner says
Reuters reports that: “’The European Union does not need Russia’s Sputnik V vaccine for COVID-19 and can achieve immunity across the continent using European production’, Thierry Breton, who heads the EU executive’s vaccine task force, told TF1 television.
“’Today, we clearly have the capacity to deliver 300 to 350 million doses by the end of June and therefore by July 14 … we have the possibility of reaching continent-wide immunity,’ he said.”
8. Ghana has vaccinated more than 420,000 people against COVID-19 in just two weeks!
WHOAFRO has tweeted this information and continued: “This covers more than 60% of the population targeted in the Greater Accra region. The country received 600,000 vaccine doses from COVAX last month.
9. EU export ban would delay UK COVID-19 vaccine drive by two months
“Britain’s COVID-19 vaccine programme faces a two-month delay in the event of an EU export ban, derailing the government’s plans to reopen the economy this summer,” an analysis for the Guardian reveals.
“The comparatively small number of doses that would be kept within the bloc would speed up the full vaccination of every adult in the EU by ‘just over a week’, the research suggests.”
10. WHO Chief: waive COVID-19 vaccine patents to put world on “war footing”
The Guardian reports: “Dr Tedros Adhanom Ghebreyesus says the world needs to be ‘on a war footing’. He supports a patent waiver that would allow countries to make and sell cheap copies of vaccines that were invented elsewhere.
“Tedros argues that the manufacturers will still get some reimbursement. ‘Waiving patents temporarily won’t mean innovators miss out. Like during the HIV crisis or in a war, companies will be paid royalties for the products they manufacture,’ he says.”